1. Metabolic Enzyme/Protease
  2. Phosphodiesterase (PDE)
  3. LEO 29102

LEO 29102 是一种有效的磷酸二酯酶 4 (phosphodiesterase 4 (PDE4)) 抑制剂,其IC50 值为 5 nM。LEO 29102 可抑制 TNFα 释放。LEO 29102 具有用于研究特应性皮炎的潜力。

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LEO 29102 Chemical Structure

LEO 29102 Chemical Structure

CAS No. : 1035572-38-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LEO 29102 is a potent phosphodiesterase 4 (PDE4) inhibitor with an IC50 value of 5 nM. LEO 29102 inhibits TNFα release. LEO 29102 has the potential for the research of atopic dermatitis[1].

IC50 & Target[1]

PDE4

5 nM (IC50)

分子量

441.31

Formula

C20H22Cl2N2O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
LEO 29102
目录号:
HY-12348
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