2. Membrane Transporter/Ion Channel Neuronal Signaling Apoptosis NF-κB Metabolic Enzyme/Protease Immunology/Inflammation MAPK/ERK Pathway
  3. Calcium Channel Apoptosis Reactive Oxygen Species p38 MAPK NF-κB
  4. Lercanidipine hydrochloride (Standard)

Lercanidipine hydrochloride (Standard)  (Synonyms: 盐酸乐卡地平(Standard))

目录号: HY-B0612AR 纯度: ≥98%
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摩尔计算器

Lercanidipine (hydrochloride) (Standard)是 Lercanidipine (hydrochloride) 的分析标准品。本产品用于研究及分析应用。Lercanidipine 是第三代、亲脂性、可穿透血脑屏障、血管选择性、具有口服活性的二氢吡啶钙通道阻断剂，pIC50 为 7.74(由 微摩尔浓度 转换而来)。Lercanidipine 具有持久的降压作用以及肾脏和神经保护作用，还具有抗氧化、抗炎和抗凋亡的特性。Lercanidipine 可用于心血管和神经学研究。

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Lercanidipine hydrochloride (Standard) Chemical Structure

Lercanidipine hydrochloride (Standard) Chemical Structure

CAS No. : 132866-11-6

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生物活性

Lercanidipine (hydrochloride) (Standard) is the analytical standard of Lercanidipine (hydrochloride). This product is intended for research and analytical applications. Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine-calcium channel blocker with a pIC50 of 7.74 (converts from μM). Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research.

分子量

648.19

Formula

C36H42ClN3O6
CAS 号
中文名称

盐酸乐卡地平(Standard)；乐卡地平盐酸盐(Standard)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Lercanidipine hydrochloride (Standard) 相关分类

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质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

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Keywords:

Lercanidipine hydrochloride (Standard)132866-11-6盐酸乐卡地平(Standard)乐卡地平盐酸盐(Standard)Calcium ChannelApoptosisReactive Oxygen Speciesp38 MAPKNF-κBCa2+ channelsCa channelsNuclear factor-κBNuclear factor-kappaBanti-oxidantanti-inflammatoryanti-apoptoticanti-hypertensiveCalcium channel blockerrenoprotectiveneuroprotectivestrokeMCAo modelVSMCSHRInhibitorinhibitorinhibit

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