2. Metabolic Enzyme/Protease
  3. Factor Xa
  4. Letaxaban

Letaxaban (TAK-442) 是一种有口服活性和选择性的直接因子 FXa 抑制剂。Letaxaban 是一种具有抗凝和抗炎双重活性的药物，通过直接抑制因子 FXa 并通过干预 PAR1 信号通路发挥作用。Letaxaban 可用于在血栓性疾病，心血管疾病和炎症相关疾病的研究。

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Letaxaban Chemical Structure

Letaxaban Chemical Structure

CAS No. : 870262-90-1

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Letaxaban 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Letaxaban (TAK-442) is an orally active and selective direct FXa inhibitor. Letaxaban is a drug with dual anticoagulant and anti-inflammatory activity that works by directly inhibiting FXa and by intervening in the PAR1 signaling pathway. Letaxaban can be used in the study of thrombotic diseases, cardiovascular diseases and inflammation-related diseases[1].

分子量

479.98

Formula

C22H26ClN3O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Letaxaban 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Letaxaban870262-90-1TAK-442TAK442TAK 442Factor XaFxaOral activityAnticoagulantAnti-inflammatoryCardiovascular diseaseFXaInhibitorinhibitorinhibit

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