2. Inhibitory Antibodies
  3. Lirilumab

Lirilumab  (Synonyms: 利瑞鲁单抗; IPH2102)

目录号: HY-P99208 纯度: 96.80%
COA

摩尔计算器

Lirilumab (IPH2102) 是一种 anti-KIR 单克隆抗体，其具有抗肿瘤活性。Lirilumab 可用于白血病、头颈部鳞状细胞癌 (SCCHN) 的研究。

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CAS No. : 1000676-41-4

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规格 价格 是否有货 数量
1 mg ￥2800
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5 mg ￥7800
In-stock
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Lirilumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lirilumab (IPH2102) is an anti-KIR monoclonal antibody, and shows antitumor activity. Lirilumab can be used in Leukemia, squamous cell carcinoma of the head and neck (SCCHN) research[1][2].

同型

Human IgG4 kappa
推荐同型对照抗体
种属

Human
体内研究
(In Vivo)

Lirilumab (intravenous injection; 15 mg/kg; once) treatment enhances survival rate of mice injected with tumor[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rag1KO-Tg KIR mice injected with tumor cells[2]
Dosage: 15 mg/kg
Administration: intravenous injection; 15 mg/kg; once
Result: Showed 6 of 7 mice survival over a 100-day period, whereas untreated or IC-treated mice all died.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

利瑞鲁单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 kappa
Biological Activity
  • Immobilized KIR2DL1 Protein, Human (HEK293, His) can bind Lirilumab. The EC50 for this effect is 16.59 ng/mL.
纯度 & 产品资料
参考文献

Lirilumab 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lirilumab1000676-41-4IPH2102利瑞鲁单抗IPH 2102IPH-2102Othersantitumor activityLeukemiasquamous cell carcinoma of the head and neckSCCHNInhibitorinhibitorinhibit

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