1. Cell Cycle/DNA Damage Epigenetics
  2. HDAC Histone Demethylase
  3. LSD1/HDAC-IN-1

LSD1/HDAC-IN-1 (compound 2) 是 HDACLSD1 的有效抑制剂,对 HDAC1HDAC2HDAC6HDAC8LSD1IC50 分别为 0.125 nM、0.373 nM、0.0118 nM、0.103 nM 和 0.571 μM。LSD1/HDAC-IN-1 在癌症研究中起着重要作用。

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LSD1/HDAC-IN-1 Chemical Structure

LSD1/HDAC-IN-1 Chemical Structure

CAS No. : 3056145-98-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LSD1/HDAC-IN-1 (compound 2) is a potent inhibitor of HDAC and LSD1, with IC50s of 0.125 nM, 0.373 nM, 0.0118 nM, 0.103 nM, and 0.571 μM for HDAC1, HDAC2, HDAC6, HDAC8 and LSD1, respectively. LSD1/HDAC-IN-1 plays an important role in cancer research[1].

IC50 & Target[1]

HDAC1

0.125 nM (IC50)

HDAC2

0.373 nM (IC50)

HDAC6

0.0118 nM (IC50)

HDAC8

0.103 nM (IC50)

LSD1

0.571 μM (IC50)

分子量

358.41

Formula

C18H18N2O4S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
LSD1/HDAC-IN-1
目录号:
HY-162955
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