1. Epigenetics Neuronal Signaling
  2. Histone Demethylase Monoamine Oxidase
  3. LSD1-IN-15

LSD1-IN-15 (compound 1b) 是一种有效的 LSD1 抑制剂。LSD1-IN-15 对LSD1-CoRESTMAO-AMAO-B 具有抑制作用,IC50 值分别为 0.149、0.028 和 0.324 μM。LSD1-IN-15 在前列腺癌 LNCaP 细胞中显示细胞生长阻滞,IC50 为 9.9 μM。

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LSD1-IN-15 Chemical Structure

LSD1-IN-15 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LSD1-IN-15 (compound 1b) is a potent LSD1 inhibitor. LSD1-IN-15 can inhibit LSD1-CoREST, MAO-A and MAO-B, with IC50 values of 0.149, 0.028, and 0.327 μM, respectively. LSD1-IN-15 displays cell growth arrest in prostate cancer LNCaP cells, with an IC50 of 9.9 μM[1].

IC50 & Target

MAO-A

0.028 ± 0. μM (IC50)

MAO-B

0.327 ± 0. μM (IC50)

分子量

328.41

Formula

C22H20N2O

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
LSD1-IN-15
目录号:
HY-144756
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