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  3. LSN3353871

LSN3353871 是一种有效的脂蛋白 a (Lp(a)) 抑制剂,可与 Kringle IV (KIV) 8、KIV7–8 和 KIV5–8 结合,Kd 分别为 756 nM、605 nM 和 423 nM。LSN3353871 可破坏 Lp(a) 的形成,IC50 为 1.69 µM。LSN3353871 具有口服生物活性。

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LSN3353871 Chemical Structure

LSN3353871 Chemical Structure

CAS No. : 2565657-20-5

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LSN3353871 is a potent inhibitor of lipoprotein(a) (Lp(a)) that can binds to Kringle IV (KIV) 8, KIV7–8 and KIV5–8, with Kd of 756 nM, 605 nM and 423 nM, respectively. LSN3353871 disrupts the formation of Lp(a) with the IC50 of 1.69 µM. LSN3353871 has oral bioactivity[1].

分子量

255.74

Formula

C13H18ClNO2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

LSN3353871 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
LSN3353871
目录号:
HY-158424
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