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  4. Lu AF58801

Lu AF58801是一种强效、可口服的脑穿透性α7烟碱型乙酰胆碱受体的正向别构调节剂，具有在小鼠观察新物体识别任务中的疗效。Lu AF58801显示出选择性地增强α7烟碱型乙酰胆碱受体的活性。Lu AF58801能够改善在接受亚慢性氟氯噻吨（PCP）处理的老鼠中的认知功能。

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Lu AF58801 Chemical Structure

Lu AF58801 Chemical Structure

CAS No. : 1531592-40-1

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Lu AF58801 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Lu AF58801 is a potent, orally available, brain-penetrant positive allosteric modulator of α7 nicotinic acetylcholine receptors with efficacy in a novel object recognition task in mice. Lu AF58801 was shown to selectively enhance the activity of α7 nicotinic acetylcholine receptors. Lu AF58801 was able to improve cognitive function in mice treated with subchronic fluchlorothiazol (PCP)[1].

分子量

325.40

Formula

C20H23NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Lu AF58801 相关分类

  • 摩尔计算器

  • 稀释计算器

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lu AF588011531592-40-1Lu AF 58801Lu AF-58801OthersInhibitorinhibitorinhibit

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产品名称：
Lu AF58801
目录号：
HY-120783
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