2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. LY53857

LY53857 是一种对血管收缩和血清素介导的 5-HT2 受体的强效拮抗剂。LY53857 以阻断对血清素的压迫反应和阻断中枢血清素受体的剂量并未降低自发性高血压大鼠 (SHR) 的平均动脉血压。此外，LY53857 能够促进大鼠输精管和豚鼠回肠神经中神经递质的释放。

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LY53857 Chemical Structure

LY53857 Chemical Structure

CAS No. : 60634-51-7

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Other Forms of LY53857:

LY53857 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LY53857 is a potent antagonist of vasoconstriction and serotonin-mediated 5-HT2 receptors. LY53857 did not reduce mean arterial blood pressure in spontaneously hypertensive rats (SHR) at doses that blocked the depressor response to serotonin and blocked central serotonin receptors. In addition, LY53857 was able to enhance neurotransmitter release in rat vas deferens and guinea pig ileal nerves[1].

分子量

500.58

Formula

C27H36N2O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LY53857 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LY5385760634-51-7LY 53857LY-538575-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorVasoconstrictionserotoninpressure responsespontaneously hypertensive ratsneurotransmittersInhibitorinhibitorinhibit

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