1. 天然产物
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  5. Lyngbyatoxin B

Lyngbyatoxin B是来自海洋蓝藻Moorea producens的多功能生物合成途径中的一种复杂化合物。通过在大肠杆菌中异源表达lyngbyatoxin生物合成途径,成功生产了lyngbyatoxin A(25.6 mg/L)及其前体indolactam-V(150 mg/L)。这种方法证实了lyngbyatoxin的生物合成路线,并为未来的途径工程奠定了化学基础。此外,成功在大肠杆菌中生产lyngbyatoxin A,为其他蓝藻天然产物的异源表达和特征鉴定提供了可能性。

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Lyngbyatoxin B Chemical Structure

Lyngbyatoxin B Chemical Structure

CAS No. : 133084-52-3

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  • 生物活性

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生物活性

Lyngbyatoxin B is a complex compound in a versatile biosynthetic pathway from the marine cyanobacterium Moorea producens. By heterologously expressing the lyngbyatoxin biosynthetic pathway in Escherichia coli, lyngbyatoxin A (25.6 mg/L) and its precursor indolactam-V (150 mg/L) were successfully produced. This approach confirmed the biosynthetic route of lyngbyatoxin and laid a chemical foundation for future pathway engineering. In addition, the successful production of lyngbyatoxin A in E. coli opens the possibility for heterologous expression and characterization of other cyanobacterial natural products.

分子量

453.62

Formula

C27H39N3O3

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献
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Lyngbyatoxin B
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