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  3. LysoFP-NO2

LysoFP-NO2 是一种定位于溶酶体的一氧化碳 (CO) 荧光探针。在溶酶体 CO 存在下,lysoFP-NO2 会转化为 lysoFP-NH2,后者具有强荧光性。LysoFP-NO2 对 CO 的选择性优于各种活性氮、氧和硫物质。它的激发/发射最大值分别为 440/528 nm,在浓度为 30 μM 时,对 HepG2 细胞无细胞毒性,最长可达 5 小时。

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LysoFP-NO2 Chemical Structure

LysoFP-NO2 Chemical Structure

CAS No. : 69408-75-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LysoFP-NO2 is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome. In the presence of lysosomal CO, lysoFP-NO2 is transformed into lysoFP-NH2, which is highly fluorescent. LysoFP-NO2 is selective for CO over various reactive nitrogen, oxygen, and sulfur species. It displays excitation/emission maxima of 440/528 nm, respectively, and is not cytotoxic to HepG2 cells for up to five hours when used at a concentration of 30 μM.

分子量

355.34

Formula

C18H17N3O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

LysoFP-NO2 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
LysoFP-NO2
目录号:
HY-130783
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