2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Lysophosphatidylethanolamines, egg

Lysophosphatidylethanolamines, egg  (Synonyms: Lyso-PE (egg); LPE (egg); L-α-lysophosphatidylethanolamine)

目录号: HY-156041 纯度: ≥99.0%
COA 产品使用指南 技术支持

Lysophosphatidylethanolamines, egg (Lyso-PE (egg); LPE (egg)) 是一种天然存在的溶血磷脂，可通过磷脂酶 A2 (PLA2) 对磷脂酰乙醇胺进行脱乙酰化而产生。它可增加 PC12 细胞中 ERK1/2 的磷酸化，这种作用可被 MEK 抑制剂 U-0126（HY-12031A）和 PD 98059（HY-12028）以及 EGFR 抑制剂 AG-1478（HY-13524）阻断。LPE 还可增加 PC12 细胞中神经突的生长和神经丝 M 的表达。LPE 可抑制部分从卷心菜中纯化的磷脂酶 D (PLD) 的活性。该产品含有溶血磷脂酰乙醇胺分子种类，其 sn-1 位具有可变的脂肪酰基链长度，sn-2 位具有羟基。

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Lysophosphatidylethanolamines, egg Chemical Structure

Lysophosphatidylethanolamines, egg Chemical Structure

CAS No. : 97281-40-8

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1 mg ￥1000
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5 mg ￥2456
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Lysophosphatidylethanolamines, egg 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 (HY-12031A) and PD 98059 (HY-12028) and the EGFR inhibitor AG-1478 (HY-13524).1 LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage.3 This product contains lysophosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position.

CAS 号
性状

固体

颜色

White to off-white

中文名称

溶血磷脂酰乙醇胺(鸡蛋)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥99.0%

COA (278 KB)

产品使用指南 (1538 KB)
参考文献

Lysophosphatidylethanolamines, egg 相关分类

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Keywords:

Lysophosphatidylethanolamines, egg97281-40-8Lyso-PE (egg) LPE (egg) L-α-lysophosphatidylethanolamine溶血磷脂酰乙醇胺(鸡蛋)Endogenous MetaboliteInhibitorinhibitorinhibit

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