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m-Chlorophenylbiguanide  (Synonyms: mCPBG)

目录号: HY-121299
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m-Chlorophenylbiguanide (mCPBG) 是一种强效高亲和力的 5-HT3 受体激动剂，对苔藓纤维-CA3 系统中的长期增强 (LTP) 具有抑制作用。m-Chlorophenylbiguanide 在浓度为 0.3-1 μM 时会减弱 LTP 的幅度，表明其在调节突触可塑性方面发挥着作用。此外，GABAA 受体拮抗剂 bicuculline 可逆转 m-Chlorophenylbiguanide 对 LTP 的影响，表明其作用与 GABAergic 神经传递之间存在联系。

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m-Chlorophenylbiguanide Chemical Structure

m-Chlorophenylbiguanide Chemical Structure

CAS No. : 48144-44-1

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m-Chlorophenylbiguanide 的其他形式现货产品:

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m-Chlorophenylbiguanide 相关抗体

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生物活性

m-Chlorophenylbiguanide (mCPBG) is a potent high-affinity agonist of the 5-HT3 receptor, exhibiting an inhibitory effect on long-term potentiation (LTP) in the mossy fiber-CA3 system. mCPBG attenuates the magnitude of LTP at concentrations of 0.3-1 microM, demonstrating its role in modulating synaptic plasticity. Additionally, the impact of mCPBG on LTP is reversible by the GABAA receptor antagonist bicuculline, indicating a connection between its action and GABAergic neurotransmission.

分子量

211.65

Formula

C8H10ClN5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

m-Chlorophenylbiguanide 相关分类

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Keywords:

m-Chlorophenylbiguanide48144-44-1mCPBGOthersInhibitorinhibitorinhibit

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