1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. Maleimide-PEG8-Val-Ala-PAB

Maleimide-PEG8-Val-Ala-PAB 是一种由可裂解的 Val-Ala-PAB (HY-125933) Linker 与探针分子 Maleimide (HY-W007324) 组成的 ADC Linker。Maleimide-PEG8-Val-Ala-PAB 可用于连接 Cetuximab (HY-P9905) 单抗和 CDK 抑制剂 SNS-032 (HY-10008),合成抗体-药物偶联物 (ADC)。

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Maleimide-PEG8-Val-Ala-PAB Chemical Structure

Maleimide-PEG8-Val-Ala-PAB Chemical Structure

1.  客户无需承担相应的运输费用。

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     可免费申领三个不同产品的试用装。

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Maleimide-PEG8-Val-Ala-PAB is an ADC linker composed of the cleavable Val-Ala-PAB (HY-125933) linker and the probe molecule Maleimide (HY-W007324). Maleimide-PEG8-Val-Ala-PAB can be used to connect Cetuximab (HY-P9905) monoclonal antibody and CDK inhibitor SNS-032 (HY-10008) to synthesize antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable ADC Linker[1]

分子量

867.98

Formula

C41H65N5O15

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Maleimide-PEG8-Val-Ala-PAB
目录号:
HY-163675
需求量: