2. Neuronal Signaling GPCR/G Protein
  3. Monoamine Oxidase 5-HT Receptor
  4. MAO-B-IN-3

MAO-B-IN-3 是一种可逆的选择性 MAO-B 抑制剂 (IC50=96 nM)。MAO-B-IN-3 还与 5-HT6R 结合，Ki 值为 696 nM。MAO-B-IN-3 可用于阿尔茨海默病的研究。

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MAO-B-IN-3 Chemical Structure

MAO-B-IN-3 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

MAO-B-IN-3 相关抗体

Top Publications Citing Use of Products

查看 Monoamine Oxidase 亚型特异性产品:

查看所有亚型
MAO-A MAO-B

查看 5-HT Receptor 亚型特异性产品:

查看所有亚型
5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

  • 生物活性

  • 纯度 & 产品资料

生物活性

MAO-B-IN-3 is a reversible and selective MAO-B inhibitor (IC50=96 nM). MAO-B-IN-3 also binds to 5-HT6R with Ki value of 696 nM. MAO-B-IN-3 can be used for research of in Alzheimer's disease[1].

IC50 & Target[1]

MAO-B

96 nM (IC50)

Human 5-HT6 Receptor

696 nM (Ki)

体外研究
(In Vitro)

MAO-B-IN-3 (1 μM) 对 MAO-A 的抑制率为 3%。在稳定表达 h5-HT6R 的 HEK293 细胞中，MAO-B-IN-3 对 5-HT6R 的 Ki 值为 696 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

MAO-B-IN-3 相关抗体:
分子量

387.47

Formula

C24H25N3O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

MAO-B-IN-3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MAO-B-IN-3Monoamine Oxidase5-HT ReceptorMAOSerotonin Receptor5-hydroxytryptamine ReceptorAlzheimer's diseasereversibleselectiveInhibitorinhibitorinhibit

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目录号：
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