1. Epigenetics Metabolic Enzyme/Protease
  2. Methionine Adenosyltransferase (MAT)
  3. MAT2A-IN-13

MAT2A-IN-13 是一种有效的口服蛋氨酸腺苷转移酶2A (MAT2A) 抑制剂,具有良好的药代动力学特征。MAT2A-IN-13在HCT-116 MTAP-缺失异种移植物模型中显示出体内效力。MAT2A-IN-13可用于 MTAP-缺失肿瘤的治疗研究。

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MAT2A-IN-13 Chemical Structure

MAT2A-IN-13 Chemical Structure

CAS No. : 2851449-24-4

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  • 生物活性

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  • 参考文献

生物活性

MAT2A-IN-13 is a potent and orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with a favorable pharmacokinetic profile. MAT2A-IN-13 shows in vivo potency in an HCT-116 MTAP-deleted xenograft model. MAT2A-IN-13 can be used for MTAP-Deleted tumors treatment research[1].

分子量

364.30

Formula

C17H12F4N4O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MAT2A-IN-13
目录号:
HY-162010
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