2. Academic Validation
  3. Larvicidal, antimycobacterial and antifungal compounds from the bark of the Peruvian plant Swartzia polyphylla DC

Larvicidal, antimycobacterial and antifungal compounds from the bark of the Peruvian plant Swartzia polyphylla DC

  • Chem Pharm Bull (Tokyo). 2006 Feb;54(2):278-9. doi: 10.1248/cpb.54.278.
Rosario Rojas 1,  Betty Bustamante,  Palmira Ventosilla,  Irma Fernádez,  Luz Caviedes,  Robert Henry Gilman,  Olga Lock,  Gerald Bruce Hammond
Affiliations

Affiliation

  • 1 Departamento de Ciencias Farmacéuticas, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru.
PMID: 16462085 DOI: 10.1248/cpb.54.278
Abstract

The 95% ethanol extract of the bark of Swartzia polyphylla DC (Fabaceae) possesses important larvicidal, antimycobacterial and Antifungal activity in vitro. Bioassay-guided studies performed on the crude ethanol extract afforded T-cadinol as the larvicidal and anti-Mycobacterium tuberculosis principle, while the Antifungal activity of the extract is due to the presence of the Flavonoids biochanin A and dihydrobiochanin A.

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