2. Academic Validation
  3. Bioactive compounds from Bauhinia purpurea possessing antimalarial, antimycobacterial, antifungal, anti-inflammatory, and cytotoxic activities

Bioactive compounds from Bauhinia purpurea possessing antimalarial, antimycobacterial, antifungal, anti-inflammatory, and cytotoxic activities

  • J Nat Prod. 2007 May;70(5):795-801. doi: 10.1021/np070010e.
Surat Boonphong 1,  Pakawan Puangsombat,  Apiwat Baramee,  Chulabhorn Mahidol,  Somsak Ruchirawat,  Prasat Kittakoop
Affiliations

Affiliation

  • 1 Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.
PMID: 17480099 DOI: 10.1021/np070010e
Abstract

Eleven new secondary metabolites (1-11), together with two known flavanones (12 and 13) and five known bibenzyls (14-18), were isolated from the root extract of Bauhinia purpurea. New compounds include eight dihydrodibenzoxepins (1-8), a dihydrobenzofuran (9), a novel spirochromane-2,1'-hexenedione (10), and a new bibenzyl (11). Antimycobacterial, antimalarial, Antifungal, cytotoxic, and anti-inflammatory activities of the isolated compounds are reported, and biosynthetic pathways of these compounds are also discussed.

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