2. Academic Validation
  3. Bioactive constituents from Chinese natural medicines. XXXII. aminopeptidase N and aldose reductase inhibitors from Sinocrassula indica: structures of sinocrassosides B(4), B(5), C(1), and D(1)-D(3)

Bioactive constituents from Chinese natural medicines. XXXII. aminopeptidase N and aldose reductase inhibitors from Sinocrassula indica: structures of sinocrassosides B(4), B(5), C(1), and D(1)-D(3)

  • Chem Pharm Bull (Tokyo). 2008 Oct;56(10):1438-44. doi: 10.1248/cpb.56.1438.
Toshio Morikawa 1,  Haihui Xie,  Tao Wang,  Hisashi Matsuda,  Masayuki Yoshikawa
Affiliations

Affiliation

  • 1 Kyoto Pharmaceutical University, Kyoto, Japan.
PMID: 18827386 DOI: 10.1248/cpb.56.1438
Abstract

From the methanolic extract of the whole plant of Sinocrassula indica (Crassulaceae), six new flavonol glycosides, sinocrassosides B(4) (1), B(5) (2), C(1) (3), D(1) (4), D(2) (5), and D(3) (6), were isolated together with 30 compounds. The structures of 1-6 were elucidated on the basis of chemical and physicochemical evidence. In addition, several constituents were found to show inhibitory effects on Aminopeptidase N and Aldose Reductase.

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