2. Academic Validation
  3. Cytotoxic pyridone alkaloids from the leaves of Piper aborescens

Cytotoxic pyridone alkaloids from the leaves of Piper aborescens

  • J Nat Prod. 1990 Nov-Dec;53(6):1575-7. doi: 10.1021/np50072a030.
C Y Duh 1,  Y C Wu,  S K Wang
Affiliations

Affiliation

  • 1 School of Pharmacy, Kaohsiung Medical College, Taiwan, Republic of China.
PMID: 2089124 DOI: 10.1021/np50072a030
Abstract

Bioactivity-guided fractionation of a CHCl3 extract of the leaves of Piper aborescens afforded a new cytotoxic pyridone alkaloid, N-(3-methoxy-4,5-methylenedioxydihydrocinnamoyl)-delta 3-pyridin-2-one [1], as well as three known cytotoxic pyridone Alkaloids, N-(3-methoxy-4,5-methylenedioxycinnamoyl)-delta 3-pyridin-2-one [2], piplartine [3], and piplartine dimer A [4].

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