2. Academic Validation
  3. Antifungal activity of sakurasosaponin from the root extract of Jacquinia flammea

Antifungal activity of sakurasosaponin from the root extract of Jacquinia flammea

  • Nat Prod Res. 2011 Jul;25(12):1185-9. doi: 10.1080/14786419.2010.511215.
K García-Sosa 1,  A Sánchez-Medina,  Sandra L Álvarez,  S Zacchino,  N C Veitch,  P Simá-Polanco,  L M Peña-Rodriguez
Affiliations

Affiliation

  • 1 Unidad de Biotecnología, Centro de Investigación Científica de Yucatán, Calle 43 No. 130 Col. Chuburná de Hidalgo, Mérida, Yucatán, 97200 México.
PMID: 21740284 DOI: 10.1080/14786419.2010.511215
Abstract

The methanolic crude extract from the roots of Jacquinia flammea showed moderate Antifungal activity against dermatophytes and very strong Antifungal activity against Colletotrichum gloeosporioides. The bioassay-guided purification of the extract, using a combination of vacuum-liquid chromatography and high performance liquid chromatography, allowed the identification of sakurasosaponin as the main metabolite responsible for the Antifungal activity.

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