1. Academic Validation
  2. Biologically active arborinane-type triterpenoids and anthraquinones from Rubia yunnanensis

Biologically active arborinane-type triterpenoids and anthraquinones from Rubia yunnanensis

  • J Nat Prod. 2011 Oct 28;74(10):2069-80. doi: 10.1021/np2002918.
Jun-Ting Fan 1 Bin Kuang Guang-Zhi Zeng Si-Meng Zhao Chang-Jiu Ji Yu-Mei Zhang Ning-Hua Tan
Affiliations

Affiliation

  • 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.
Abstract

Twelve new arborinane-type triterpenoids (1-12) and four new Anthraquinones (13-16), together with 50 known compounds, were isolated from the roots of Rubia yunnanensis. The structures of 1-16 were elucidated by spectroscopic data analysis and chemical methods. All compounds were evaluated for their cytotoxic, Antibacterial, and Antifungal activities. Rubiyunnanol C (5) is the first example of an arborinane-type triterpenoid with a double bond at C-8-C-9.

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