2. Academic Validation
  3. Quinaldopeptin, a novel antibiotic of the quinomycin family

Quinaldopeptin, a novel antibiotic of the quinomycin family

  • J Antibiot (Tokyo). 1990 Jul;43(7):796-808. doi: 10.7164/antibiotics.43.796.
S Toda 1,  K Sugawara,  Y Nishiyama,  M Ohbayashi,  N Ohkusa,  H Yamamoto,  M Konishi,  T Oki
Affiliations

Affiliation

  • 1 Bristol-Myers Research Institute, Ltd., Tokyo Research Center, Japan.
PMID: 2387774 DOI: 10.7164/antibiotics.43.796
Abstract

Quinaldopeptin, a new type of quinomycin Antibiotic, was isolated from the culture of Streptoverticillium album strain Q132-6. The Antibiotic exhibited strong in vitro antimicrobial and cytotoxic activity and significantly prolonged the survival time of mice inoculated with a murine tumor. Quinaldopeptin is a symmetric cyclic peptide linked only by peptide bonds and differs from known Antibiotics of the quinomycin family by the lack of ester linkage.

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