1. Academic Validation
  2. Chemical constituents from Bletilla striata and their NO production suppression in RAW 264.7 macrophage cells

Chemical constituents from Bletilla striata and their NO production suppression in RAW 264.7 macrophage cells

  • J Asian Nat Prod Res. 2018 Apr;20(4):385-390. doi: 10.1080/10286020.2017.1339696.
Yang Zhao 1 Jun-Jie Niu 1 2 Xiao-Chen Cheng 1 Yu-Xin Lu 1 Xiao-Feng Jun 1 Xi-Rong Zhao 2 Qing-Lin Zhang 1 Chu-Tse Wu 1
Affiliations

Affiliations

  • 1 a Department of Experimental Hematology , Beijing Institute of Radiation Medicine , Beijing 100850 , China.
  • 2 b College of Life Science and Food Engineering, Huaiyin Institute of Technology , Huai'an 223003 , China.
Abstract

A novel glucoside bletilloside A (1) was isolated from the tubers of Bletilla striata, together with seven known compounds (2-8). Their structures were determined on the basis of extensive spectroscopic analyses. All compounds were evaluated for the inhibition on NO production effects in RAW 264.7 macrophage cells, while militarine (4) and dactylorhin A (5) exhibited moderate inhibitory effects.

Keywords

Bletilla striata; Glucosides; NO production; Orchidaceae.

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