2. Academic Validation
  3. Arizonins, a new complex of antibiotics related to kalafungin. I. Taxonomy of the producing culture, fermentation and biological activity

Arizonins, a new complex of antibiotics related to kalafungin. I. Taxonomy of the producing culture, fermentation and biological activity

  • J Antibiot (Tokyo). 1988 Sep;41(9):1205-11. doi: 10.7164/antibiotics.41.1205.
J P Karwowski 1,  M Jackson,  R J Theriault,  J F Prokop,  M L Maus,  C F Hansen,  D M Hensey
Affiliations

Affiliation

  • 1 Anti-infective Research Division, Abbott Laboratories, North Chicago, Illinois.
PMID: 3182401 DOI: 10.7164/antibiotics.41.1205
Abstract

The arizonins, a novel complex of Antibiotics related to kalafungin, were discovered in the fermentation broth of Actinoplanes sp. AB660D-122. Comparative taxonomic studies indicated that the culture is a new species and therefore has been designated Actinoplanes arizonaensis sp. nov. Two members of the complex, arizonins A1 and B1, exhibit moderate to potent in vitro antimicrobial activity against pathogenic strains of Gram-positive bacteria.

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