Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation

Affiliations

• 1 Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL 60637, USA.
• 2 Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL 60637, USA; Medical Scientist Training Program, The University of Chicago, Chicago, IL 60637, USA.
• 3 Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
• 4 Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL 60637, USA.
• 5 Department of Medicine, The University of Chicago, Chicago, IL 60637, USA.
• 6 China Medical University, Taichung 404, Taiwan.
• 7 Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL 60637, USA; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA. Electronic address: chuanhe@uchicago.edu.