Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy

Affiliations

• 1 Institute of Clinical Neurobiology, University Hospital Würzburg, Würzburg, Germany.
• 2 Institute for Food Quality and Safety, Research Group Food Toxicology and Alternative/Complementary Methods to Animal Experiments, University of Veterinary Medicine Hannover, Hannover, Germany.
• 3 Bloomberg School of Public Health, Center for Alternatives to Animal Testing, Johns Hopkins University, Baltimore, MD, USA.
• 4 Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH16 4SB, UK.
• 5 UK Dementia Research Institute at University of Edinburgh, University of Edinburgh, Edinburgh, EH16 4SB, UK.
• 6 Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, Edinburgh, EH16 4SB, UK.
• 7 Center for Regenerative Therapies TU Dresden, Fetscherstr. 105, 01307, Dresden, Germany.
• 8 Medical Faculty Carl Gustav Carus of TU Dresden, Dresden, Germany.
• 9 Department of Neurology, Hannover Medical School, Hannover, Germany.
• 10 Imaging Core Facility, Biocenter, University of Würzburg, 97074, Würzburg, Germany.
• 11 Core Unit Systems Medicine, University of Würzburg, D-97080, Würzburg, Germany.
• 12 Translational Neurodegeneration Section Albrecht-Kossel, Department of Neurology, University Medical Center Rostock, Rostock, Germany.
• 13 Center for Transdisciplinary Neurosciences Rostock, University Medical Center Rostock, Rostock, Germany.
• 14 Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) Rostock/Greifswald, 18147, Rostock, Germany.
• 15 Institute of Biochemistry, Christian-Albrechts-University Kiel, Olshausenstr. 40, 24098, Kiel, Germany.
• 16 Institute of Clinical Neurobiology, University Hospital Würzburg, Würzburg, Germany. Lueningsch_P@ukw.de.
• # Contributed equally.