1. Academic Validation
  2. A new taxane diterpenoid from Taxus mairei

A new taxane diterpenoid from Taxus mairei

  • J Nat Prod. 1998 Jun 26;61(6):838-40. doi: 10.1021/np970573y.
Y C Shen 1 C Y Chen Y H Kuo
Affiliations

Affiliation

  • 1 Institute of Marine Resources, National Sun Yat-sen University, 70 Lien-Hai Road, Kaohsiung, Taiwan, Republic of China.
Abstract

A new 11(15-->1)-abeotaxane diterpene, taxumairol K (1), has been isolated from the ethanolic extract of the roots of Formosan Taxus mairei (Lemee & Levl.) S. Y. Hu. The structure of 1 was determined as 9alpha-(benzoyloxy)-2alpha,4alpha- diacetoxy-5beta ,20-epoxy-1beta, 7beta,10beta,13alpha-tetrahydroxy-11(15-->1)-abeota xane on the basis of spectral analysis. Taxumairol K (1) exhibited mild cytotoxicity against HeLa tumor cells.

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