2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. Mesyl Salvinorin B

Mesyl Salvinorin B 是一种有效的选择性 kappa 阿片受体 (kappa opioid receptor (KOP-r)) 激动剂。Mesyl Salvinorin B 可预防小鼠的 ADE (酒精剥夺效应)。Mesyl Salvinorin B 剂量依赖性地降低 CED (慢性饮酒递增) 小鼠的酒精摄入量和偏好。

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Mesyl Salvinorin B Chemical Structure

Mesyl Salvinorin B Chemical Structure

CAS No. : 862073-79-8

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规格 价格 是否有货 数量
500 μg ￥2052
3 - 4 周

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Mesyl Salvinorin B 相关抗体

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μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mesyl Salvinorin B is a potent and selective kappa opioid receptor (KOP-r) agonist. Mesyl Salvinorin B prevents the ADE (Alcohol deprivation effect) in mice. Mesyl Salvinorin B dose-dependently reduces alcohol intake and preference in CED (chronic escalation drinking) mice[1][2].

体内研究
(In Vivo)

Mesyl Salvinorin B (0.3, 1, 3 mg/kg; i.p.; once) 3 mg/kg 时可在雄性和雌性小鼠中预防ADE[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 8 weeks, Male and female adult C57BL/6J mice[1]
Dosage: 0.3, 1, 3 mg/kg
Administration: I.p.; once
Result: Showed less intake than the vehicle-treated ones in the ADE (Alcohol deprivation effect) session at 3 mg/kg.
分子量

468.52

Formula

C22H28O9S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Mesyl Salvinorin B 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mesyl Salvinorin B862073-79-8Opioid ReceptorInhibitorinhibitorinhibit

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