1. 天然产物
  2. 植物 生物碱
  3. 豆科 菊科 吡咯类生物碱
  4. 非洲紫檀
  5. Methyl pheophorbide a

Methyl pheophorbide a 

目录号: HY-N10902 纯度: 99.57%
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Methyl pheophorbide a 是一种天然产物,叶绿素 a 衍生物之一。

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Methyl pheophorbide a Chemical Structure

Methyl pheophorbide a Chemical Structure

CAS No. : 5594-30-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Methyl pheophorbide a is a natural product, one of the chlorophyll-a derivatives[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
1A9 ED50
0.26 μg/mL
Compound: 5
Cytotoxicity against human 1A9 cells after 72 hrs by SRB assay
Cytotoxicity against human 1A9 cells after 72 hrs by SRB assay
[PMID: 11473423]
A549 ED50
0.83 μg/mL
Compound: 5
Cytotoxicity against human A549 cells after 72 hrs by SRB assay
Cytotoxicity against human A549 cells after 72 hrs by SRB assay
[PMID: 11473423]
Daudi IC50
25 μM
Compound: 6, mPheo
Cytotoxicity against human Daudi cells under deem light after 96 hrs by MTT assay
Cytotoxicity against human Daudi cells under deem light after 96 hrs by MTT assay
[PMID: 17993275]
HCT-8 ED50
1 μg/mL
Compound: 5
Cytotoxicity against human HCT8 cells after 72 hrs by SRB assay
Cytotoxicity against human HCT8 cells after 72 hrs by SRB assay
[PMID: 11473423]
HeLa IC50
0.182 μM
Compound: 7, MPa
Photosensitizing activity against human HeLa cells assessed as reduction in cell viability pre-incubated for 24 hrs followed by 15 mins exposure to 670 to 710 nm light at dose of 2.0 J/cm2 and measured 12 hrs after radiation by WST-8 assay
Photosensitizing activity against human HeLa cells assessed as reduction in cell viability pre-incubated for 24 hrs followed by 15 mins exposure to 670 to 710 nm light at dose of 2.0 J/cm2 and measured 12 hrs after radiation by WST-8 assay
[PMID: 25797162]
HeLa IC50
25 μM
Compound: 6, mPheo
Cytotoxicity against human HeLa cells under deem light after 96 hrs by MTT assay
Cytotoxicity against human HeLa cells under deem light after 96 hrs by MTT assay
[PMID: 17993275]
K562 IC50
> 100 μM
Compound: 6, mPheo
Cytotoxicity against human K562 cells under deem light after 96 hrs by MTT assay
Cytotoxicity against human K562 cells under deem light after 96 hrs by MTT assay
[PMID: 17993275]
KB ED50
0.23 μg/mL
Compound: 5
Cytotoxicity against human KB cells after 72 hrs by SRB assay
Cytotoxicity against human KB cells after 72 hrs by SRB assay
[PMID: 11473423]
MCF7 ED50
0.95 μg/mL
Compound: 5
Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
[PMID: 11473423]
NCI-H69 IC50
> 100 μM
Compound: 6, mPheo
Cytotoxicity against human H69 cells under deem light after 96 hrs by MTT assay
Cytotoxicity against human H69 cells under deem light after 96 hrs by MTT assay
[PMID: 17993275]
Raji IC50
> 100 μM
Compound: 6, mPheo
Cytotoxicity against human Raji cells under deem light after 96 hrs by MTT assay
Cytotoxicity against human Raji cells under deem light after 96 hrs by MTT assay
[PMID: 17993275]
SiHa IC50
> 100 μM
Compound: 6, mPheo
Cytotoxicity against human SIHA cells under deem light after 96 hrs by MTT assay
Cytotoxicity against human SIHA cells under deem light after 96 hrs by MTT assay
[PMID: 17993275]
SK-MEL ED50
1.2 μg/mL
Compound: 5
Cytotoxicity against human SK-MEL cells after 72 hrs by SRB assay
Cytotoxicity against human SK-MEL cells after 72 hrs by SRB assay
[PMID: 11473423]
分子量

606.71

Formula

C36H38N4O5

CAS 号
性状

固体

颜色

Brown to black

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Methyl pheophorbide a
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