2. Anti-infection
  3. SARS-CoV
  4. Methyl tanshinonate

Methyl tanshinonate 是一种丹参酮，可以从丹参 (S. miltiorriza) Bunge (唇形科)中分离出来。Mmethyl tanshinonate 是 SARS-CoV 中 Mpro 酶的有效抑制剂 (IC50 = 21.1 µM)。Methyl tanshinonate 可用于糖尿病和 SARS-CoV 研究。

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Methyl tanshinonate Chemical Structure

Methyl tanshinonate Chemical Structure

CAS No. : 18887-19-9

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规格 价格 是否有货 数量
1 mg ￥3950
1 - 2 周
5 mg 现货 1 - 2 周
10 mg   询价  
50 mg   询价  

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Methyl tanshinonate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Methyl tanshinonate is a tanshinone, that can be isolated from Salvia miltiorrhiza (S. miltiorrhiza) Bunge (Lamiaceae). Methyl tanshinonate is a potent inhibitor of Mpro enzyme in SARS-CoV (IC50 = 21.1 µM). Methyl tanshinonate can be used for diabetes and SARS-CoV research[1][2][3].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
AGS IC50
> 50 μM
Compound: 5, methyl tanshinonate
Viability of human AGS cells under normoxic conditions after 24 hrs by MTT assay
Viability of human AGS cells under normoxic conditions after 24 hrs by MTT assay
[PMID: 17583950]
AGS IC50
7.48 μM
Compound: 5, methyl tanshinonate
Inhibition of HIF1 activation in human AGS cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay
Inhibition of HIF1 activation in human AGS cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay
[PMID: 17583950]
Hep 3B2 IC50
> 50 μM
Compound: 5, methyl tanshinonate
Viability of human Hep3B cells under normoxic conditions after 24 hrs by MTT assay
Viability of human Hep3B cells under normoxic conditions after 24 hrs by MTT assay
[PMID: 17583950]
Hep 3B2 IC50
7.34 μM
Compound: 5, methyl tanshinonate
Inhibition of HIF1 activation in human Hep3B cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay
Inhibition of HIF1 activation in human Hep3B cells assessed as inhibition of hypoxia-induced luciferase expression after 16 hrs by reporter assay
[PMID: 17583950]
分子量

338.35

Formula

C20H18O5
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Methyl tanshinonate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methyl tanshinonate18887-19-9SARS-CoVSARS coronavirusInhibitorinhibitorinhibit

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