2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. MHY 553

MHY 553 是一种可口服的 PPARα 激动剂，通过增加脂肪酸氧化和减少衰老过程中的炎症来缓解肝脂肪变性。MHY553 抑制了肝 X 受体激动剂在 HepG2 细胞中诱导的甘油三酯积累。MHY553 显著抑制老年大鼠的炎症 mRNA 表达。

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MHY 553 Chemical Structure

MHY 553 Chemical Structure

CAS No. : 6265-56-1

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MHY 553 相关抗体

Top Publications Citing Use of Products

查看 PPAR 亚型特异性产品:

查看所有亚型
PPARα PPARβ/δ PPARγ PPAR PPARδ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MHY 553 is an oral PPARα agonist that alleviates liver steatosis by increasing fatty acid oxidation and reducing inflammation during the aging process. MHY553 inhibits triglyceride accumulation induced by liver X receptor agonists in HepG2 cells. MHY553 significantly suppresses inflammatory mRNA expression in aged rats[1].

分子量

243.28

Formula

C13H9NO2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MHY 553 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MHY 5536265-56-1MHY553MHY-553PPARPeroxisome proliferator-activated receptorsHepG2aged ratsinflammatoryInhibitorinhibitorinhibit

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目录号：
HY-128135
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