2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. MIDD0301 sodium

MIDD0301 sodium  (Synonyms: GL-II-93 sodium)

目录号: HY-123801A
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MIDD0301 (GL-II-93) sodium 是一种口服有效的 γ-氨基丁酸 A 型受体 (GABAAR) 抑制剂和抗哮喘剂。MIDD0301 sodium 在小鼠中表现出生物和免疫毒理学安全性，不会影响循环淋巴细胞、单核细胞和粒细胞数量。MIDD0301 sodium 在重复剂量下无明显不良免疫反应，好于 Prednisone (HY-B0214)。MIDD0301 sodium 可放松组胺收缩的豚鼠和人气管平滑肌，用于支气管收缩疾病的研究。

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MIDD0301 sodium Chemical Structure

MIDD0301 sodium Chemical Structure

CAS No. : 2593569-36-7

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MIDD0301 sodium 的其他形式现货产品:

Other Forms of MIDD0301 sodium:

MIDD0301 sodium 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MIDD0301 (GL-II-93) is an orally available, active γ-aminobutyric acid type A receptor (GABAAR) inhibitor and anti-asthmatic agent. MIDD0301 exhibits biological and immunotoxicological safety in mice and does not affect the number of circulating lymphocytes, monocytes, and granulocytes. MIDD0301 has no significant adverse immune response at repeated doses, which is better than Prednisone (HY-B0214). MIDD0301 relaxes histamine-contracted guinea pig and human airway smooth muscle and is used in the study of bronchoconstrictive diseases[1][2].

IC50 & Target

GABAAR[1]
分子量

436.21

Formula

C19H12BrFN3NaO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MIDD0301 sodium 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MIDD03012593569-36-7GL-II-93MIDD 0301MIDD-0301GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorInhibitorinhibitorinhibit

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