2. Apoptosis
  3. Apoptosis
  4. Minnelide free base

Minnelide free base 是雷公藤甲素 (HY-32735) 的衍生物，在许多肿瘤类型 (特别是在胰腺癌) 中显示出抗肿瘤 (antitumor) 活性。 Minnelide 可导致凋亡 (apoptosis)。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Minnelide free base Chemical Structure

Minnelide free base Chemical Structure

CAS No. : 1254885-39-6

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Minnelide free base 的其他形式现货产品:

Other Forms of Minnelide free base:

Minnelide free base 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Minnelide free base is a prodrug of Triptolide (HY-32735) that shows potent antitumor activity in a number of tumor types, particularly in pancreatic cancer. Minnelide free base promotes apoptosis[1].

体外研究
(In Vitro)

Minnelide (0-200 nM；48 小时) free base 在存在磷酸酶的情况下处理后，胰腺癌细胞系的细胞活力显著降低，但在不存在磷酸酶的情况下则没有降低[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Minnelide free base 相关抗体:
体内研究
(In Vivo)

Minnelide (腹膜内注射；0.1-0.6 mg/kg；每日一次或每日两次) free base 导致治疗结束时肿瘤重量和体积显着减少，并增加 MIA PaCa-2 衍生的人类胰腺肿瘤的胰腺癌原位模型的生存率[2]。
Minnelide (腹膜内注射；0.42 mg/kg；每日一次；28 天) free base 可防止局部扩散，并导致转移性 S2-013 细胞的胰腺癌异种移植模型的平均肿瘤重量下降[2]。
Minnelide (腹膜内注射；0.42 mg/kg、0.21 mg/kg；每日一次) free base 导致 SCID 小鼠中的异种移植肿瘤消退，表现出纤维化和固缩核[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

470.41

Formula

C21H27O10P
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Minnelide free base 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Minnelide1254885-39-6ApoptosisInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Minnelide free base
目录号：
HY-124584A
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z