2. Others Neuronal Signaling Membrane Transporter/Ion Channel Metabolic Enzyme/Protease Apoptosis Anti-infection
  3. Antibiotic Calcium Channel Isotope-Labeled Compounds Potassium Channel HIF/HIF Prolyl-Hydroxylase Bacterial MDM-2/p53 Apoptosis
  4. Minocycline-d7

Minocycline-d7  (Synonyms: 米诺环素-d7(主要))

目录号: HY-W654013
产品使用指南 技术支持

Minocycline-d7 是氘代标记的 Minocycline。Minocycline 是一种口服有效、能透过血脑屏障的半合成四环素类抗生素。Minocycline 是一种缺氧诱导因子 (HIF-1α) 抑制剂。Minocycline 具有抗癌(anti-cancer)，抗炎(anti-inflammatory) 和谷氨酸 (glutamate) 拮抗作用。Minocycline 降低谷氨酸神经传递，显示神经保护特性和抗抑郁作用。Minocycline 通过与细菌核糖体 30S 亚基结合，抑制细菌蛋白的合成，从而产生抑菌 (bacteriostatic) 作用。

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Minocycline-d<sub>7</sub> Chemical Structure

Minocycline-d7 Chemical Structure

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Other Forms of Minocycline-d7:

Minocycline-d7 相关抗体

Top Publications Citing Use of Products

查看 Antibiotic 亚型特异性产品:

查看所有亚型
Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

查看 Calcium Channel 亚型特异性产品:

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

查看 HIF/HIF Prolyl-Hydroxylase 亚型特异性产品:

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HIF-1α HIF

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Minocycline-d7 is deuterium labeled Minocycline. Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect[1][2][3][4][5][6][7][8].

分子量

464.52

Formula

C23H20D7N3O7
非标记 CAS
中文名称

米诺环素-d7(主要)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Minocycline-d7 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Minocycline-d7米诺环素-d7(主要)AntibioticCalcium ChannelIsotope-Labeled CompoundsPotassium ChannelHIF/HIF Prolyl-HydroxylaseBacterialMDM-2/p53ApoptosisCa2+ channelsCa channelsKcsAHypoxia-inducible factorsHIFsHIF-PHInhibitorinhibitorinhibit

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