2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. MK-2295

MK-2295 (NGD-8243) 是一种 TRPV1 拮抗剂。MK-2295 是一种镇痛剂，可用于疼痛研究。

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MK-2295 Chemical Structure

MK-2295 Chemical Structure

CAS No. : 573678-04-3

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规格 价格 是否有货 数量
1 mg ￥2590
1 - 2 周
5 mg ￥5845
1 - 2 周
10 mg 现货 1 - 2 周
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Customer Review

MK-2295 相关抗体

Top Publications Citing Use of Products

查看 TRP Channel 亚型特异性产品:

查看所有亚型
TRPC TRPM TRPV TRPA TRPML

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MK-2295 (NGD-8243) is a TRPV1 antagonist. MK-2295 is an analgesic agent, and can be used for research of pain[1][2].

IC50 & Target

TRPV1

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 IC50
1.1 nM
Compound: 6a
Antagonist activity at human recombinant TRPV1 expressed in HEK293 cells assessed as inhibition of capsazepine-induced calcium mobilization by FLIPR assay
Antagonist activity at human recombinant TRPV1 expressed in HEK293 cells assessed as inhibition of capsazepine-induced calcium mobilization by FLIPR assay
[PMID: 20307063]
分子量

434.34

Formula

C21H12F6N4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MK-2295 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MK-2295573678-04-3NGD-8243MK2295MK 2295NGD8243NGD 8243TRP ChannelTransient receptor potential channelsanalgesicInhibitorinhibitorinhibit

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目录号：
HY-W517163
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