1. Metabolic Enzyme/Protease
  2. MMP
  3. MMP-2 Inhibitor-4

MMP-2 Inhibitor-4 (Compound 5g) 是一种 MMP-2 抑制剂,IC50 为 152.62 nM。MMP-2 Inhibitor-4 可通过与 MMP-2 活性位点稳定结合来降低 K562 细胞系中的 MMP-2 水平,且在 ACHN 细胞系中显示出强烈的抗血管生成效果。MMP-2 Inhibitor-4 有望用于慢性髓性白血病 (CML) 研究。

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MMP-2 Inhibitor-4 Chemical Structure

MMP-2 Inhibitor-4 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MMP-2 Inhibitor-4 (Compound 5g) is an MMP-2 inhibitor with an IC50 of 152.62 nM. MMP-2 Inhibitor-4 can reduce the levels of MMP-2 in the K562 cell line through stable binding at the MMP-2 active site, and it demonstrates strong antiangiogenic effects in the ACHN cell line. MMP-2 Inhibitor-4 holds promise for research in chronic myeloid leukemia (CML)[1].

IC50 & Target

MMP-2

152.62 nM (IC50)

分子量

405.47

Formula

C19H23N3O5S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MMP-2 Inhibitor-4
目录号:
HY-170604
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