1. Metabolic Enzyme/Protease
  2. Liposome
  3. mono-Pal-MTO

mono-Pal-MTO 是一种抗癌活性分子米托蒽醌 (MTO) 与棕榈油酸结合生成的棕榈油基脂质,当摩尔比为 1:1 的 mono-Pal-MTO 和 di-Pal-MTO 的纳米颗粒联用,可以显示出有效的 siRNA 细胞递送,并增强抗癌活性。

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mono-Pal-MTO Chemical Structure

mono-Pal-MTO Chemical Structure

CAS No. : 1349197-89-2

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
1 mg ¥800
1 - 2 周
5 mg ¥2000
1 - 2 周
10 mg ¥3200
1 - 2 周
50 mg   询价  
100 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

mono-Pal-MTO is a palm oil-based lipid produced by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity[1].

体外研究
(In Vitro)

Delivery of Mcl-1-specific anticancer siRNA (siMcl-1) using nanoparticles of mono-Pal-MTO and di-Pal-MTO (md11-Pal-MTO) in a 1:1 molar ratio enhances in vitro antitumour activity, reducing tumour cell viability by 81% and tumour size by 83%. Lipofectamine 2000-mediated transfection with siMcl-1 reduces tumour cell viability by 68%[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

680.87

Formula

C38H56N4O7

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
mono-Pal-MTO
目录号:
HY-148701
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