1. Immunology/Inflammation Apoptosis Cell Cycle/DNA Damage Autophagy Membrane Transporter/Ion Channel Neuronal Signaling
  2. FKBP Calcium Channel
  3. MP-010

MP-010 是一种 FKBP12 配体,通过稳定 RyR 通道活性发挥细胞质钙调节作用。MP-010 可促进 SOD1G93A 小鼠肌萎缩侧索硬化症 (ALS) 功能改善,表现为运动协调能力改善,神经肌肉接头的完整性增加,以及脊髓运动神经元存活率显著上升。MP-010 可用于神经疾病领域的研究。

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MP-010 Chemical Structure

MP-010 Chemical Structure

CAS No. : 3024617-59-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MP-010 is a FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. MP-010 promotes functional improvement in SOD1G93A amyotrophic lateral sclerosis (ALS) mice, as evidenced by improved motor coordination, increased integrity of neuromuscular junctions, and significantly enhanced survival of spinal motor neurons. MP-010 can be used for research in the field of neurological diseases[1].

分子量

308.40

Formula

C14H20N4O2S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MP-010
目录号:
HY-172152
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