2. Stem Cell/Wnt
  3. Hippo (MST)
  4. MR24

MR24 是一种 G-5555 (HY-19635) 衍生物，是一种哺乳动物 STE20 样 (MST)激酶抑制剂。MR24 选择性靶向 MST3/4，EC50 值分别为 57 和 583 nM。

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MR24 Chemical Structure

MR24 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

MR24 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MR24, a G-5555 (HY-19635) derivative, is a mammalian STE20-like (MST) kinase inhibitor. MR24 selectively target MST3/4, with EC50 values of 57 and 583 nM, respectively[1].

IC50 & Target

IC50: 57 ± 44 nM (MST3), 583 ± 210 nM (MST4)[1]
体外研究
(In Vitro)

MR24 (10 μM, 24-72 h) 导致细胞周期停滞在 G1 期[1]。
MR24 在 1 小时内表现出超过 90% 的优异微粒体稳定性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

MR24 相关抗体:

Cell Cycle Analysis[1]

Cell Line: HCT116 cells
Concentration: 10 μM
Incubation Time: 24, 48, and 72 h
Result: Increased the fraction of cells in the G1 phase.
分子量

509.00

Formula

C26H29ClN6O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MR24 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MR24MR 24MR-24Hippo (MST)HCT116 cellsmicrosomal stabilitymammalian STE20-like kinaseMSTInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-157932
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