2. Membrane Transporter/Ion Channel
  3. P2X Receptor
  4. MRS 2219

MRS 2219  (Synonyms: Pyridoxol, cyclic 3,4-hydrogen phosphate)

目录号: HY-102063
产品使用指南

摩尔计算器

MRS 2219 (Pyridoxol) 是 P2X1 受体 的选择性药理学探针。MRS 2219 选择性增强 P2X1 受体的 ATP 诱发反应，EC50 为 5.9 μM。

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MRS 2219 Chemical Structure

MRS 2219 Chemical Structure

CAS No. : 14141-47-0

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MRS 2219 相关抗体

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P2X1 Receptor P2X2 Receptor P2X3 Receptor P2X4 Receptor P2X7 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MRS 2219 (Pyridoxol) is a selective pharmacological probe of P2X1 receptor. MRS 2219 selectively potentiated ATP-evoked responses at P2X1 receptors with an EC50 of 5.9 μM[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Oocyte EC50
5.9 μM
Compound: 12
Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytes
Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytes
[PMID: 11462975]
分子量

231.14

Formula

C8H10NO5P
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MRS 2219 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MRS 221914141-47-0Pyridoxol, cyclic 3,4-hydrogenMRS2219MRS-2219P2X ReceptorP2XRsInhibitorinhibitorinhibit

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