1. Anti-infection
  2. Bacterial
  3. Mycobacterial Zmp1-IN-1

Mycobacterial Zmp1-IN-1 是一种分枝杆菌锌金属蛋白酶-1 (Zmp1) 抑制剂。Mycobacterial Zmp1-IN-1 对 Mtb H37Ra 具有剂量依赖性抑制的抗分枝杆菌活性。Mycobacterial Zmp1-IN-1 可用于结核病 (TB) 的研究。

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Mycobacterial Zmp1-IN-1 Chemical Structure

Mycobacterial Zmp1-IN-1 Chemical Structure

CAS No. : 3033421-29-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mycobacterial Zmp1-IN-1 is a mycobacterial zinc metalloprotease-1 (Zmp1) inhibitor. Mycobacterial Zmp1-IN-1 has anti-mycobacterial activity for Mtb H37Ra in dose-dependent inhibition. Mycobacterial Zmp1-IN-1 can be used for the research of tuberculosis (TB)[1].

体外研究
(In Vitro)

Mycobacterial Zmp1-IN-1 (Compound 2f)对 M. bovisMtb H37Ra具有剂量依赖性的抗分枝杆菌活性[1]
Mycobacterial Zmp1-IN-1 对 RAW 264.7 和 MRC-5 细胞系无急性细胞毒性,IC50 值均 >128 μM[1]
Mycobacterial Zmp1-IN-1(8 μM,32 μM,128 μM)诱导巨噬细胞宿主细胞内细菌存活率的降低[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

525.57

Formula

C26H27N3O7S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Mycobacterial Zmp1-IN-1 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Mycobacterial Zmp1-IN-1
目录号:
HY-152035
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