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  4. N-Hydroxysuccinimide

N-Hydroxysuccinimide  (Synonyms: HOSu; 1-Hydroxy-2,5-pyrrolidinedione)

目录号: HY-Y0623 纯度: 99.73%
COA 产品使用指南

摩尔计算器

N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) 是一种常用于生物共轭技术的活化酯，例如荧光染料和酶的蛋白质标记、色谱支持物、微珠、纳米粒子和微阵列载玻片的表面活化，以及化学合成肽。

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N-Hydroxysuccinimide Chemical Structure

N-Hydroxysuccinimide Chemical Structure

CAS No. : 6066-82-6

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规格 价格 是否有货 数量
5 g ￥100
In-stock
10 g ￥170
In-stock
50 g   询价  

* Please select Quantity before adding items.

Customer Review

N-Hydroxysuccinimide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is an activated ester commonly used in bioconjugation technologies such as protein labeling with fluorescent dyes and enzymes, chromatography supports, beads, nanoparticles, and microarrays Surface activation of glass slides, and chemically synthesized peptides[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 EC50
> 50 μM
Compound: NHS
Cytotoxicity against human HEK293 cells assessed as inhibition of cell viability incubated for 30 mins by cell titer-glo assay
Cytotoxicity against human HEK293 cells assessed as inhibition of cell viability incubated for 30 mins by cell titer-glo assay
[PMID: 35859867]
HEK293 IC50
> 50 μM
Compound: NHS
Cytotoxicity against human HEK293 cells assessed as inhibition of cell viability incubated for 30 mins in presence of CRBN-tracer by nanoBRET assay
Cytotoxicity against human HEK293 cells assessed as inhibition of cell viability incubated for 30 mins in presence of CRBN-tracer by nanoBRET assay
[PMID: 35859867]
HEK293 IC50
> 50 μM
Compound: NHS
Cytotoxicity against permeabilized HEK293 cells assessed as inhibition of cell viability incubated for 30 mins in presence of CRBN-tracer by nanoBRET assay
Cytotoxicity against permeabilized HEK293 cells assessed as inhibition of cell viability incubated for 30 mins in presence of CRBN-tracer by nanoBRET assay
[PMID: 35859867]
分子量

115.09

Formula

C4H5NO3
CAS 号
性状

固体

颜色

White to off-white

中文名称

N-羟基琥珀酰亚胺； N-羟基丁二酰亚胺
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 100 mg/mL (868.89 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 8.6889 mL 43.4443 mL 86.8885 mL
5 mM 1.7378 mL 8.6889 mL 17.3777 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.99%

COA (271 KB) HNMR (126 KB) RP-HPLC (226 KB)

产品使用指南 (1538 KB)
参考文献

N-Hydroxysuccinimide 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 8.6889 mL 43.4443 mL 86.8885 mL 217.2213 mL
5 mM 1.7378 mL 8.6889 mL 17.3777 mL 43.4443 mL
10 mM 0.8689 mL 4.3444 mL 8.6889 mL 21.7221 mL
15 mM 0.5793 mL 2.8963 mL 5.7926 mL 14.4814 mL
20 mM 0.4344 mL 2.1722 mL 4.3444 mL 10.8611 mL
25 mM 0.3476 mL 1.7378 mL 3.4755 mL 8.6889 mL
30 mM 0.2896 mL 1.4481 mL 2.8963 mL 7.2407 mL
40 mM 0.2172 mL 1.0861 mL 2.1722 mL 5.4305 mL
50 mM 0.1738 mL 0.8689 mL 1.7378 mL 4.3444 mL
60 mM 0.1448 mL 0.7241 mL 1.4481 mL 3.6204 mL
80 mM 0.1086 mL 0.5431 mL 1.0861 mL 2.7153 mL
100 mM 0.0869 mL 0.4344 mL 0.8689 mL 2.1722 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Hydroxysuccinimide6066-82-6HOSu 1-Hydroxy-2,5-pyrrolidinedioneN-羟基琥珀酰亚胺 N-羟基丁二酰亚胺Biochemical Assay ReagentsInhibitorinhibitorinhibit

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目录号：
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