1. 天然产物
  2. 植物 酚类
  3. 苋科 多酚类
  4. 喜旱莲子草
  5. N-trans-Feruloyl-3-methyldopamine

N-trans-Feruloyl-3-methyldopamine 

目录号: HY-N3191
产品使用指南

N-trans-Feruloyl-3-methyldopamine (compound 4) 是一种抗癌化合物,可从莲心草 (Alternanthera philoxeroides) 中分离得到。N-trans-Feruloyl-3-methyldopamine Hela 细胞具有细胞毒性,在 30 μg/mL 浓度下的抑制率为 72.2%。

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N-trans-Feruloyl-3-methyldopamine Chemical Structure

N-trans-Feruloyl-3-methyldopamine Chemical Structure

CAS No. : 78510-19-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

N-trans-Feruloyl-3-methyldopamine (compound 4) is an anticancer compound isolated from Alternanthera philoxeroides. N-trans-Feruloyl-3-methyldopamine is cytotoxic to HeLa cells, with an inhibition rate of 72.2% at a concentration of 30 μg/mL[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
BV-2 IC50
> 50 μM
Compound: 29
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess assay
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess assay
[PMID: 33822610]
RAW264.7 IC50
> 50 μM
Compound: 26
Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess reagent based assay
Antiinflammatory activity in mouse RAW264.7 assessed as inhibition of LPS-induced NO production preincubated for 30 mins followed by LPS stimulation measured after 24 hrs by Griess reagent based assay
[PMID: 33939429]
分子量

343.37

Formula

C19H21NO5

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

N-trans-Feruloyl-3-methyldopamine 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
N-trans-Feruloyl-3-methyldopamine
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HY-N3191
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