2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. N6-Aminoadenosine

N6-Aminoadenosine 是一种腺嘌呤核苷类似物。腺苷类似物大多可作为平滑肌血管扩张剂，也被证明能够抑制癌症进展。这一系列的热门产品有 Adenosine phosphate，Acadesine (HY-13417)，Clofarabine (HY-A0005)，Fludarabine phosphate (HY-B0028) 和 Vidarabine (HY-B0277)。

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N6-Aminoadenosine Chemical Structure

N6-Aminoadenosine Chemical Structure

CAS No. : 5746-27-0

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N6-Aminoadenosine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

N6-Aminoadenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Caco-2 GI50
1.03 μM
Compound: 5
Antiproliferative activity against human Caco2 cells after 72 hrs by MTS assay
Antiproliferative activity against human Caco2 cells after 72 hrs by MTS assay
[PMID: 21349610]
HeLa GI50
0.52 μM
Compound: 5
Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay
[PMID: 21349610]
HT-29 GI50
1.44 μM
Compound: 5
Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
[PMID: 21349610]
K562 GI50
0.61 μM
Compound: 5
Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
[PMID: 21349610]
MCF7 GI50
0.35 μM
Compound: 5
Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
[PMID: 21349610]
分子量

282.26

Formula

C10H14N6O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

N6-Aminoadenosine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N6-Aminoadenosine5746-27-0Nucleoside Antimetabolite/Analogmuscle vasodilatorInhibitorinhibitorinhibit

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目录号：
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