2. Cell Cycle/DNA Damage
  3. NEKs
  4. Nek2-IN-4

Nek2-IN-4 是一种有效的 NEK2 抑制剂，IC50 值为 15 nM。Nek2-IN-4 抑制细胞增殖。Nek2-IN-4 具有胰腺癌研究的潜力。

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Nek2-IN-4 Chemical Structure

Nek2-IN-4 Chemical Structure

CAS No. : 2225902-88-3

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规格 价格 是否有货
1 mg ￥5680
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Customer Review

Nek2-IN-4 相关抗体

Top Publications Citing Use of Products

查看 NEKs 亚型特异性产品:

查看所有亚型
NEK1 NEK2 NEK6 NEK7

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Nek2-IN-4 is a potent NEK2 inhibitor with an IC50 value of 15 nM. Nek2-IN-4 inhibits cell proliferation. Nek2-IN-4 has the potential for the research of pancreatic cancer[1].

IC50 & Target

NEK2

15 nM (IC50)

体外研究
(In Vitro)

Nek2-IN-4 (72 h) 抑制细胞生长，对 AsPC-1、PL45、MIA PaCa-2 细胞的 IC50 值分别为 0.064、0.031、0.161 µM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Nek2-IN-4 相关抗体:

Cell Proliferation Assay[1]

Cell Line: AsPC-1, PL45, MIA PaCa-2 cells
Concentration:
Incubation Time: 72 h
Result: Showed antiproliferative activity with IC50s of 0.064, 0.031, 0.161 µM for AsPC-1, PL45, MIA PaCa-2 cells, respectively.
分子量

568.61

Formula

C28H27F3N6O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Nek2-IN-4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nek2-IN-42225902-88-3NEKsNIMA–related KinasesNIMA (never in mitosis gene a)-related Expressed KinasesAsPC-1PL45MIA PaCa-2antiproliferativepancreatic cancerInhibitorinhibitorinhibit

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目录号：
HY-137046
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