2. Anti-infection
  3. Parasite Bacterial Fungal
  4. Neocryptolepine

Neocryptolepine  (Synonyms: Cryptotackieine)

目录号: HY-E70250
产品使用指南

摩尔计算器

Neocryptolepine (Cryptotackieine) 具有抗疟原虫活性。Neocryptolepine 还表现出对革兰氏阳性菌的抗菌活性 (MIC < 100 μg/mL) 和抗真菌活性。

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Neocryptolepine Chemical Structure

Neocryptolepine Chemical Structure

CAS No. : 114414-78-7

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Neocryptolepine 相关抗体

Top Publications Citing Use of Products

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Neocryptolepine (Cryptotackieine) has antiplasmodial activity. Neocryptolepine also shows antibacterial activity against Gram-positive bacteria (MIC < 100 μg/mL), and antifungal activity[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Ehrlich IC50
0.54 nM
Compound: 15
Cytotoxicity against mouse Ehrlich cells assessed as cell growth inhibition incubated for 3 hrs by trypan blue exclusion assay
Cytotoxicity against mouse Ehrlich cells assessed as cell growth inhibition incubated for 3 hrs by trypan blue exclusion assay
[PMID: 34710743]
L6 IC50
3194 nM
Compound: Neocryptolepine
Toxicity against rat L6 cells after 72 hrs by Alamar blue assay
Toxicity against rat L6 cells after 72 hrs by Alamar blue assay
[PMID: 23360309]
L6 IC50
3194 nM
Compound: II, cryptotackieine, Neocryptolepine
Cytotoxicity against rat L6 cells assessed as growth inhibition after 70 hrs by Alamar blue staining-based inverted microscopic analysis
Cytotoxicity against rat L6 cells assessed as growth inhibition after 70 hrs by Alamar blue staining-based inverted microscopic analysis
[PMID: 23685569]
MRC5 IC50
11 μM
Compound: 15
Antiproliferative activity against human MRC5 cells assessed as cell growth inhibition incubated for 7 days by MTT assay
Antiproliferative activity against human MRC5 cells assessed as cell growth inhibition incubated for 7 days by MTT assay
[PMID: 34710743]
MRC5 IC50
11 μM
Compound: 1a
Cytotoxicity against human diploid embryonic lung cell line MRC-5 using MTT assay
Cytotoxicity against human diploid embryonic lung cell line MRC-5 using MTT assay
[PMID: 12139461]
MRC5 IC50
11 μM
Compound: 3, (Neocryptolepine, Cryptotackieine)
Cytotoxicity against human MRC5 SV2 cells after 72 hrs by resazurin-based fluorometric assay
Cytotoxicity against human MRC5 SV2 cells after 72 hrs by resazurin-based fluorometric assay
[PMID: 19364118]
分子量

232.28

Formula

C16H12N2
CAS 号
中文名称

新白叶藤碱
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Neocryptolepine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Neocryptolepine114414-78-7Cryptotackieine新白叶藤碱ParasiteBacterialFungalantiplasmodialantibacterialGram-positiveantifungalInhibitorinhibitorinhibit

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