1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Nephrin

Nephrin  (Synonyms: Hopane-6α,7β,22-triol)

目录号: HY-118173
产品使用指南

Nephrin (Hopane-6α,7β,22-triol)是一种细胞表面信号受体蛋白,具有调节足细胞功能的活性。Nephrin在肾脏过滤屏障的正常功能中发挥着重要作用。Nephrin与β细胞生存信号相关,有助于维持细胞存活。Nephrin的尿液水平可能与肾小管损伤相关,并且可以作为早期急性肾损伤的生物标志物。

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Nephrin Chemical Structure

Nephrin Chemical Structure

CAS No. : 65136-96-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Nephrin (Hopane-6α,7β,22-triol) is a cell surface signaling receptor protein with activity in regulating podocyte function. Nephrin plays an important role in the normal function of the kidney's filtration barrier. Nephrin is associated with beta cell survival signals and helps maintain cell survival. Urinary levels of nephrin may be associated with tubular injury and can serve as a biomarker for early acute kidney injury[1].

分子量

460.73

Formula

C30H52O3

CAS 号
结构分类
初始来源

Nephroma species

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Nephrin
目录号:
HY-118173
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