2. Immunology/Inflammation
  3. NOD-like Receptor (NLR)
  4. NLRP3-IN-56

NLRP3-IN-56 (compound 062) 是 NLRP3 抑制剂。NLRP3-IN-56 强效抑制 THP-1 细胞分泌 IL-1β 的水平，IC50 为 9.7 nM。NLRP3-IN-56 可用于 NLRP3 介导的症状和/或疾病的研究。

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NLRP3-IN-56 Chemical Structure

NLRP3-IN-56 Chemical Structure

CAS No. : 3048421-42-4

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NLRP3-IN-56 相关抗体

Top Publications Citing Use of Products

查看 NOD-like Receptor (NLR) 亚型特异性产品:

查看所有亚型
NLRP3 NLRP1 NOD1 NOD2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NLRP3-IN-56 (compound 062) is a NLRP3 inhibitor. NLRP3-IN-56 potently inhibits the level of IL-1β secretion by THP-1 cells with an IC50 of 9.7 nM. NLRP3-IN-56 can be used for the study of NLRP3-mediated symptoms and/or diseases[1].

分子量

383.83

Formula

C20H18ClN3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NLRP3-IN-56 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NLRP3-IN-563048421-42-4NOD-like Receptor (NLR)NLRP3 inhibitorIL-1β secretionNLRP3-mediated symptomsInhibitorinhibitorinhibit

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产品名称：
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目录号：
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