1. Signaling Pathways
  2. Immunology/Inflammation
  3. NOD-like Receptor (NLR)
  4. NOD-like Receptor (NLR) Inhibitors

NOD-like Receptor (NLR) Inhibitors

NLRP3

NLRP1

NOD1

NOD2

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Please try each isoform separately.

NOD-like Receptor (NLR) Degraders, Inhibitors, Agonists, Antagonists & Activators
Product Name NLRP3 NLRP1 NOD1 NOD2 Purity
Nigericin sodium salt
NLRP3
      99.37%
MCC950 sodium
NLRP3
      99.75%
MCC950
NLRP3
      99.62%
Nigericin
NLRP3
      99.37%
INF 195
NLRP3
      99.55%
CY-09
NLRP3
      98.01%
QS-21
NLRP3 inflammasome
      99.67%
Muramyl dipeptide  
NLRP1
    ≥98.0%
Trimethylamine N-oxide
NLRP3
      ≥98.0%
GSK717      
NOD2
99.88%
NLRP3/AIM2-IN-3
NLRP3
      98.00%
Dapansutrile
NLRP3
      ≥98.0%
Stavudine
NLRP3
      99.87%
BMS-986299
NLRP3, EC50: 1.28 μM
      99.76%
Muscone
NLRP3
      ≥98.0%
Selnoflast
NLRP3
      98.58%
NOD-IN-1    
NOD1
NOD2
99.56%
Mifamurtide      
NOD2
≥99.0%
Ruscogenin
NLRP3
      99.59%
Licochalcone B
NLRP3
      99.93%
Trimethylamine N-oxide dihydrate
NLRP3
      ≥98.0%
Arglabin
NLRP3
      99.87%
CORM-3
NLRP3
     
JC2-11
NLRP3 inflammasome
      98.02%
YQ128
NLRP3, IC50: 0.30 μM
      99.83%
NLRP3-IN-13
NLRP3
      99.01%
4'-Methoxyresveratrol
NLRP3
      99.48%
Britannin
NLRP3, IC50: 3.630 μM
      99.93%
Soyasaponin II
NLRP3 inflammasome
      99.81%
Emlenoflast
NLRP3 inflammasome, IC50: <100 nM
      98.19%
(±)11(12)-EET
NLRP3 inflammasome
      98.3%
Emlenoflast sodium
NLRP3 inflammasome, IC50: <100 nM
      98.76%
L6H21
NLRP3 inflammasome
      99.46%
Mifamurtide sodium      
NOD2
98.19%
Oxidized ATP trisodium salt
NLRP3 inflammasome
      ≥98.0%
NVP-DFV890
NLRP3
      98.47%
NLRP3-IN-18
NLRP3, IC50: ≤1.0 μM
      98.06%
HMGB1-IN-1
NLRP3
      99.37%
Moronic acid
NLRP3
      98.6%
NP3-562
NLRP3, IC50: 214 nM
      98.16%
Articaine hydrochloride
NLRP3
      99.38%
NLRP3-IN-11
NLRP3, IC50: <0.3 μM
      98.79%
BAL-0028
NLRP3, IC50: 25 nM
     
NLRP3-IN-17
NLRP3 inflammasome, IC50: 7 nM
      99.23%
SLC3037
NLRP3
      99.85%
JC-171
NLRP3
      98.41%
INF4E
NLRP3
      99.38%
NOD2 antagonist 1      
NOD2, IC50: 5.23 μM
99.57%
Mifamurtide TFA      
NOD2
≥98.0%
NLRP3-IN-NBC6
NLRP3, IC50: 574 nM
      99.40%
NT-0249
NLRP3
     
NDT-30805
NLRP3 inflammasome
NLRP3
     
TLR7 agonist 27      
NOD2, EC50: 6156 nM
NOD1-IN-1    
NOD1, IC50: 33 nM
 
NLRP3-IN-9
NLRP3
     
NLRP3-IN-38
NLRP3 inflammasome, EC50: 23 nM
     
NOD1 antagonist-1    
NOD1, IC50: 9.18 μM
NOD2, IC50: 20.8 μM
Articaine
NLRP3
     
NLRP3-IN-32
NLRP3 inflammasome
     
P2Y14R antagonist 1
NLRP3
     
AMS-17
NLRP3
     
NOD2 agonist 3      
NOD2, EC50: 111.45 nM
MC1
NLRP3, Kd: 19.3 nM
     
NOD1/2-IN-1    
NOD1, IC50: 18 nM
NOD2, IC50: 170 nM
JT001
NLRP3
     
NLRP3-IN-4
NLRP3
     
NOD1/2 antagonist-1    
NOD1, IC50: 1.13 μM
NOD2, IC50: 0.77 μM
NLRP3-IN-45
NLRP3 inflammasome
     
NLRP3-IN-15
NLRP3 inflammasome
     
JT001 sodium
NLRP3
     
NLRP3-IN-6
NLRP3 inflammasome
     
RC529-MDP      
NOD2
NP3-146
NLRP3
     
NLRP3-IN-42
NLRP3, Kd: 1.15 μM
     
NLRP3-IN-16
NLRP3 inflammasome
     
MR2938
NLRP3
     
α-Glucosidase/NLRP3-IN-1
NLRP3
     
NLRP3-IN-55
NLRP3, IC50: 0.34 μM
NLRP3, Kd: 0.45 μM
     
NLRP3-IN-36
NLRP3, IC50: <1 μM
     
NLRP3-IN-7
NLRP3 inflammasome
     
NLRP3-IN-14
NLRP3 inflammasome, Kd: 5.87 μM
     
NLRP3-IN-41
NLRP3
     
SBN-284
NLRP3 inflammasome, EC50: 1 μM
     
NLRP3-IN-8
NLRP3 inflammasome
NLRP3
     
MC-ND-18
NLRP3, DC50: 125.5 nM
     
Stavudine sodium
NLRP3